Persistent pain: It’s the same as if you ride a bike a lot, you get better at riding a bike. Play the piano a lot, you get better at it. Send danger messages a lot, you get better at it. That’s an adaptation, and the same thing occurs in the brain.

Catalyst investigates recent advances in science and medical engineering that are transforming our understanding of chronic pain and opening the door to new treatments in the hope of bringing relief to so many people.